ANIMAL-FREE CHEMICAL SAFETY ASSESSMENT

New approach methodologies (NAM), such as in chemico and in vitro assays, and in silico models, are often used within Integrated Approaches to Testing and Assessment (IATA), Defined Approaches (DA) and Next-Generation Risk Assessment (NGRA) to provide information on hazard and risk in chemical safety assessment. Despite a strong scientific basis, barriers remain to regulatory uptake of these tools. We are addressing those barriers by positioning NAMs as the primary paradigm in chemical safety assessment through legal, regulatory and scientific means and by providing scientific support to address urgent regulatory needs.