ANIMAL-FREE CHEMICAL SAFETY ASSESSMENT
ANIMAL-FREE CHEMICAL SAFETY ASSESSMENT
Supporting animal-free innovation in the chemicals sector
New approach methodologies (NAM), such as in chemico and in vitro assays, and in silico models, are often used within Integrated Approaches to Testing and Assessment (IATA), Defined Approaches (DA) and Next-Generation Risk Assessment (NGRA) to provide information on hazard and risk in chemical safety assessment. Despite a strong scientific basis, barriers remain to regulatory uptake of these tools. We are addressing those barriers by positioning NAMs as the primary paradigm in chemical safety assessment through legal, regulatory and scientific means and by providing scientific support to address urgent regulatory needs.

About animal-free chemical safety assessment
We’re positioning NAMs as the primary paradigm in chemical safety assessment and developing educational resources to support long-term acceptance and use of NAMs in IATA, DA and NGRA.

Promoting regulatory acceptance
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Meet our collaborators
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12th World Congress on Alternatives and Animal Use in the Life Sciences

Monocyte Activation Test the experience of the Italian Institute of Health
Workstream Coordinators

Jay Ingram
HSI Director, Chemicals
Research & Toxicology Department
Email: jingram@hsi.org

Donna Macmillan, PhD
HSI Senior Principal Strategist, Regulatory Science,
Research & Toxicology Department
Email: dmacmillan@hsi.org