Animal-Free Safety Assessment (AFSA)

Imagine a world without animal testing… where the safety of chemicals, cosmetics, therapeutics and other products is assured using modern, human biology-based predictive tools. Making this world a reality is the goal of the AFSA Collaboration.

“I predict that 10 years from now, safety testing for newly developed drugs…will be largely carried out using human biochips…This approach…will mostly replace animal testing for drug toxicity and environmental sensing, giving results that are more accurate, at lower cost and with higher throughput.”
- Francis Collins, MD, PhD
Director, U.S. National Institutes of Health, 2016

“I predict that 10 years from now, safety testing for newly developed drugs…will be largely carried out using human biochips…This approach…will mostly replace animal testing for drug toxicity and environmental sensing, giving results that are more accurate, at lower cost and with higher throughput.”


- Francis Collins, MD, PhD
Director, U.S. National Institutes of Health, 2016

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  • The AFSA Collaboration brings together corporate and non-profit leaders who share the goal of accelerating a modern, species-relevant approach to safety assessment globally to better protect people and our planet, and hasten the replacement of animal testing
    READ MORE
  • “I predict that 10 years from now, safety testing for newly developed drugs…will be largely carried out using human biochips…This approach…will mostly replace animal testing for drug toxicity and environmental sensing, giving results that are more accurate, at lower cost and with higher throughput.”

    Francis Collins, MD, PhD
    Director, U.S. National Institutes of Health 2016
    READ MORE

The Animal-Free Safety Assessment (AFSA) Collaboration brings together corporate and non-profit leaders who share the goal of accelerating a modern, species-relevant approach to safety assessment globally to better protect people and our planet, and hasten the replacement of animal testing. Meet our members: 

The Animal-Free Safety Assessment (AFSA) Collaboration brings together corporate and non-profit leaders who share the goal of accelerating a modern, species-relevant approach to safety assessment globally to better protect people and our planet, and hasten the replacement of animal testing. Meet our members:

Future Leaders Travel Grants

AFSA Collaboration partners provide travel grants to early career scientists who are pursuing a career in animal-free toxicology or research.

Removing Obsolete Vaccine Animal Tests

It's time to say good-bye to animal tests for abnormal toxicity, target animal batch safety and pyrogenicity – worldwide.

 

Are You AOP Trained?

Explore our continuing education materials – your one-stop shop for online training and connecting to global Adverse Outcome Pathway development efforts.

Next-Generation Risk Assessment

We’re developing a new curriculum to help companies and regulators assess cosmetic safety without any new animal data.

The overt and hidden use of animal-derived products in alternative methods for skin sensitisation: a systematic review

Marigliani B, Sehn FP, Silva JVMA, Balottin LBL, Augusto EFP, Buehler AM

Global harmonization of vaccine testing requirements: Making elimination of the ATT and TABST a concrete global achievement

Viviani L, Halder M, Gruber M, Bruckner L, Cußler K, Sanyal G, Srinivas G, Goel S, Kaashoek M, Litthauer D, Lopes da Silva A, Sakanyan E, Aprea P, Jin H, Vandeputte J, Seidle T, Yakunin D

Workshop on the validation and regulatory acceptance of innovative 3R approaches in regulatory toxicology – Evolution versus revolution

Burgdorf T, Piersma AH, Landsiedel R, Clewell R, Kleinstreuer N, Oelgeschläger M, Desprez B, Kienhuis A, Bosh P, de Vries R, de Wit L, Seidle T, Scheel J, Schönfelder G, van Benthem J, Vinggaard AM, Eskes C, Ezendam J
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