scientist-toxicology-testing-afsa-webinar

Webinar: Integrated Approaches to Testing and Assessment

Online Webinar - Hosted in Republic of Korea
22nd October 2020

Co-hosts: National Institute of Food and Drug Safety Evaluation, Humane Society International, AFSA Collaboration

AGENDA (English)

AGENDA (Korean)

This online event will present the current uses, potential applications, and future perspective of the Integrated Approaches to Testing and Assessment (IATA). The event will feature presentations from South Korean regulatory bodies, industry and universities, together with a leading representative of the global consumer goods industry.

(WEBEX link to come)

IATAs are targeted and efficient testing strategies for chemical hazard or risk characterization, which follow an iterative and integrative approach to answer a defined question with the required certainty in a specific regulatory context. Different types of information from existing sources, new testing (e.g., in chemico, in vitro, and in vivo), and non-testing (e.g., in silico), can be considered as needed, and evaluated using Weight of Evidence in an iterative process. Hypothesis formation, testing strategy, data weighing and integration can also be supported by Adverse Outcome Pathways (AOPs), which are expected to provide insight into the biological relevance, reliability and uncertainties associated with the results from the different test methods for regulatory use. Development and application of AOP-informed IATA represent the current state-of-the-art for evaluating and generating information to meet different regulatory purposes, shifting from traditional toxicity testing in animals to a more tailored, thoughtful and predictive approach, which takes into account mechanistic data at various levels of biological organization.

Integrated Approaches to Toxicology and Assessment (IATA) – The Future of Regulatory Toxicology Assessment

Schedule (All times are South Korean GMT +9)

15:00-15:15
Welcome remarks
In-soon Nam, Member of National Assembly
Jayoung Jeong, Director of Toxicological Evaluation and Research Department, National Institute of Food and Drug Safety Evaluation

Introduction
Borami Seo, Humane Society International/Korea

15:15-15:30
General introduction to IATA
Ilseob Shim, National Institute of Environmental Research

15:30-15:50
IATA research cases
Seung Min Oh, Hoseo University

15:50-16:15
Use of IATA for Next Generation Risk Assessment (NGRA) decision-making
Gavin Maxwell, Unilever *5 min. Q&A if time allows

16:15-16:35
Practical use of IATA for eye irritation and sensitization
Susun An, Amore Pacific

16:35-16:55
AOP-informed IATA Development for Regulatory Purposes: A Case Study on Thyroid Hormone Disruption
Kyungho Choi, Seoul National University

16:55-17:10
Q&A
Chair: Seung Min Oh, Hoseo University
Closing
Borami Seo, Humane Society International/Korea

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