Safety assessment of cosmetics is exposure-led. The ability to fully understand in-use scenarios and the subsequent local and systemic exposure metrics can inform the degree of hazard data needed to support a risk assessment. This module covers initial considerations when setting up an exposure assessment, where to find consumer use data, how to estimate exposure using deterministic approaches, how to refine the estimate using probabilistic modeling, and how to approach aggregate exposure.
Presented by AFSA Collaboration members:
Christina Hickey, Firmenich
David Sheffield, Unilever
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