Animal-Free Safety Assessment (AFSA)

Home_page_hero

LATEST NEWS:
First of its kind AFSA master class in animal-free safety assessment for cosmetics launched
Register >>

Home_page_hero

Imagine a world without animal testing… where the safety of chemicals, cosmetics, therapeutics and other products is assured using modern, human biology-based predictive tools. Making this world a reality is the goal of the AFSA Collaboration.

“I predict that 10 years from now, safety testing for newly developed drugs…will be largely carried out using human biochips…This approach…will mostly replace animal testing for drug toxicity and environmental sensing, giving results that are more accurate, at lower cost and with higher throughput.”

Francis Collins, MD, PhD
Director, U.S. National Institutes of Health 2016

The Animal-Free Safety Assessment (AFSA) Collaboration is a unique multi-sector partnership between non-profit, corporate, and philanthropic leaders working to advance acceptance and use of animal-free safety science as a gold standard across regulatory frameworks worldwide. Meet our members:

The Animal-Free Safety Assessment (AFSA) Collaboration brings together corporate and non-profit leaders who share the goal of accelerating a modern, species-relevant approach to safety assessment globally to better protect people and our planet, and hasten the replacement of animal testing. Meet our members:

AFSA Master Class

The AFSA Collaboration has developed this Master Class in animal-free safety assessment of cosmetics to build confidence and capacity in the use of animal-free data in safety decision-making.

learn more

Canada to phase out chemical toxicity testing on animals

The Canadian Government has passed historic amendments to the Canadian Environmental Protection Act, committing to developing a roadmap to prioritize animal-free testing methods and phase out chemical toxicity testing on animals by 2035.

REACHing for solutions

Watch our webinar and read our peer-reviewed paper outlining our recommendations to revise EU chemicals regulation and modernise safety assessment.

webinar & paper

South Korea to include recombinant Factor C in the pharmacopoeia

The synthetic alternative for the Bacterial Endotoxin Test will be added in the Korean Pharmacopoeia. Another country is recognizing the sustainable choice to move away from horseshoe crabs derived reagent.

Victory! Canada bans cosmetics animal testing

Canada has passed a ban on cosmetics animal testing and the sale of products that rely on new animal test data to substantiate their safety.

Biologicals publication: Event series on animal testing alternative for vet vaccines

In collaboration with IABS, and veterinary industry association, HelathforAnimals, we hosted an event series on the implementation and regulatory acceptance of non-animal testing for veterinary vaccines’ batch release testing.

pulication

Latest Events

View All

REACHing for solutions: Essential revisions to the EU chemicals regulation to modernise safety assessment

Pereira M, Macmillan DS, Willett C, Seidle T.

Publisher’s website

Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients

Dent MP, Vaillancourt E, Thomas RS, Carmichael PL, Ouedraogo G, Kojima H, Barroso J, Ansell J, Barton-Maclaren TS, Bennekou SH, Boekelheide K, Ezendam J, Field J, Fitzpatrick S, Hatao M, Kreiling R, Lorencini M, Mahony C, Montemayor B, Mazaro-Costa R, Oliveira J, Rogiers V, Smegal D, Taalman R, Tokura Y, Verma R, Willett C, C. Yang

Publisher’s website

Systematic Review to Compare Chemical Hazard Predictions of the Zebrafish Embryotoxicity Test With Mammalian Prenatal Developmental Toxicity

Hoffmann S, Marigliani B, Akgün-Ölmez SG, Ireland D, Cruz R, Busquet F, Flick B, Lalu M, Ghandakly EC, de Vries RBM, Witters H, Wright RA, Ölmez M, Willett C, Hartung T, Stephens ML, Tsaioun KA

Publisher’s website

> View All

Animal-Free Safety Assessment (AFSA)

The Animal-Free Safety Assessment (AFSA) Collaboration is a unique multi-sector partnership between non-profit, corporate, and philanthropic leaders working to advance acceptance and use of animal-free safety science as a gold standard across regulatory frameworks worldwide. Meet our members:

AFSA Master Class

Canada to phase out chemical toxicity testing on animals

REACHing for solutions

South Korea to include recombinant Factor C in the pharmacopoeia

Victory! Canada bans cosmetics animal testing

Biologicals publication: Event series on animal testing alternative for vet vaccines

Latest Events

12th World Congress on Alternatives and Animal Use in the Life Sciences

Monocyte Activation Test the experience of the Italian Institute of Health

Toward implementation plans for replacement of animal testing for human vaccines

How to resolve inconclusive predictions from defined approaches for skin sensitisation in OECD Guideline No. 497

3Rs Implementation in Veterinary Vaccine Batch-Release Testing: Current state-of-the-art and future opportunities

REACHing for solutions: Essential revisions to the EU chemicals regulation to modernise safety assessment

REACHing for solutions: Essential revisions to the EU chemicals regulation to modernise safety assessment

Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients

Systematic Review to Compare Chemical Hazard Predictions of the Zebrafish Embryotoxicity Test With Mammalian Prenatal Developmental Toxicity