Animal-Free Safety Assessment (AFSA)


AFSA master class in animal-free cosmetic safety assessment launched on 10th anniversary of EU Ban


Imagine a world without animal testing… where the safety of chemicals, cosmetics, therapeutics and other products is assured using modern, human biology-based predictive tools. Making this world a reality is the goal of the AFSA Collaboration.

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The Animal-Free Safety Assessment (AFSA) Collaboration is a unique multi-sector partnership between non-profit, corporate, and philanthropic leaders working to advance acceptance and use of animal-free safety science as a gold standard across regulatory frameworks worldwide. Meet our members: 

The Animal-Free Safety Assessment (AFSA) Collaboration brings together corporate and non-profit leaders who share the goal of accelerating a modern, species-relevant approach to safety assessment globally to better protect people and our planet, and hasten the replacement of animal testing. Meet our members:

Master Class in Animal-Free Safety Assessment

Our free online certificate course is designed to help cosmetics stakeholders assure consumer safety without animal testing.

Driving Legal Reforms for Cosmetics Worldwide

We're spearheading efforts to outlaw cosmetics animal testing and trade in key global markets by 2024.

Removing Obsolete Vaccine Animal Tests

We’ve built a global community of engaged stakeholders who support replacement and deletion of specific animal tests.

Are You AOP Trained?

Explore our continuing education materials – your one-stop shop for online training and connecting to global Adverse Outcome Pathway development efforts.

REACHing for solutions: Essential revisions to the EU chemicals regulation to modernise safety assessment

Pereira M, Macmillan DS, Willett C, Seidle T.

Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients

Dent MP, Vaillancourt E, Thomas RS, Carmichael PL, Ouedraogo G, Kojima H, Barroso J, Ansell J, Barton-Maclaren TS, Bennekou SH, Boekelheide K, Ezendam J, Field J, Fitzpatrick S, Hatao M, Kreiling R, Lorencini M, Mahony C, Montemayor B, Mazaro-Costa R, Oliveira J, Rogiers V, Smegal D, Taalman R, Tokura Y, Verma R, Willett C, C. Yang

Systematic Review to Compare Chemical Hazard Predictions of the Zebrafish Embryotoxicity Test With Mammalian Prenatal Developmental Toxicity

Hoffmann S, Marigliani B, Akgün-Ölmez SG, Ireland D, Cruz R, Busquet F, Flick B, Lalu M, Ghandakly EC, de Vries RBM, Witters H, Wright RA, Ölmez M, Willett C, Hartung T, Stephens ML, Tsaioun KA
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