Capacity building: AFSA Education and Training Program in NGRA

Capacity building: AFSA Education and Training Program in NGRA - AFSA

Science has advanced rapidly in recent years, rendering safety assessment of certain products and substances not just possible, but actual in some circumstances. This is especially true in the area of cosmetic safety assessment, where animal testing bans have fueled urgency in the development and use of non-animal methods. 

Training Program

To complement legislative efforts to end cosmetic animal testing, we are developing training materials to build capacity in the application of animal-free ‘next generation risk assessment’ (NGRA). This will support the development of new and safer projects, as well as robust safety decisions.

  • Safety assessment of cosmetics and cosmetic ingredients without new animal data
  • All aspects of the process for internal and regulatory safety assessments
  • Covers the spectrum of available tools as well as some tools in development
  • Focuses on understanding the information generated from the tools and how to use this information vs. how to perform or build the individual methods
  • Address the needs of regulatory & regulated communities, CROs & other stakeholders
  • Support regional capacity-building to achieve long-term acceptance & implementation of animal-free approaches 

The course is relevant to any stakeholder that makes a decision regarding chemical safety, including:

  • government and industry safety assessors
  • small and medium enterprises
  • contract research organizations & consultants

The modules include content and learning objectives for both novice and expert audiences.

Watch a video about this initiative:

NGRA & Training Modules Overview

NGRA is an exposure-led, hypothesis-driven risk assessment approach that integrates all types of information, relying prominently on new approach methods (NAMs – defined as methods that do not involve animals), in an iterative process designed specifically for the substance and the question being asked.

To create the AFSA E&T course modules, we have taken the complete NGRA process and divided it into eight modules for content development as diagrammed below. A cross-cutting ninth module covers the state of the global regulatory environment for cosmetics and chemicals.

NGRA Risk assessment and training diagram
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